Prognostic and Diagnostic Value of Pancreatic Stone Protein (PSP) in Septic Intensive Care Unit (ICU) Patients

Document Type : Original Article

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Department of Clinical Pathology, faculty of medicine, Aswan University

Abstract

Background: Sepsis is a condition caused by the dysregulation of the host response to infection, and known as life-threatening organ dysfunction.
Aim: To estimate of the pancreatic stone protein level in intensive care unit septic manifestation and prognostic and diagnostic value of pancreatic stone protein.
Patients and methods: This prospective case control research has been performed at Aswan University Hospital.
Results: Pearson’s correlation coefficients (r) between procalcitonin level and C- reactive protein (CRP) was 0.348, with a strong positive relationship between the two variables. Pearson’s correlation coefficients (r) between procalcitonin level and blood culture (positive) were 0.197, with a strong positive relationship between the two variables. Pearson’s correlation coefficients (r) between pancreatic stone protein level and blood culture (positive) were -0.098, with a weak negative relationship between the two variables.
Conclusion: Procalcitonin is a reliable predictor of mortality and a marker for sepsis, while pancreatic stone protein is limited in critically sick cases for diagnosing sepsis, but its performance is comparable to other biomarkers like CRP and PCT.

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Aswan University Medical Journal
Volume 4, Issue 3
December 2024
Pages 74-83

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